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Alzheimer's disease (AD) is a neurodegenerative disorder that affects the brain and is characterized by the gradual loss of cognitive and neurological abilities.
The disease is progressive. Over time, it slowly destroys memory, thinking and social skills, and limits the patient’s ability to conduct a basic conversation. Eventually, patients lose the ability to conduct the simplest daily tasks.
As Alzheimer’s progresses, some of these complications can affect other physical functions of the body, such as swallowing, balance ...
Cannabis may help treat or prevent Alzheimer’s because it contains cannabinoids that may reduce the amount of beta-amyloid plaques in the brain.
The most two common cannabinoids available in cannabis are CBD and THC. Both components have the same chemical formula and together they can help fight Alzheimer’s disease. The main difference between these two ingredients is that CBD has little or no effect on cognition compared to THC.
Cannabis is composed of many different cannabinoids. The main active ingredients include:
1- the psychoactive cannabinoid delta-9-tetrahydrocannabinol or THC
2- the non-psychoactive cannabidiol or CBD.
Cannabis works to treat or reduce the symptoms of Alzheimer’s by:
1- Reducing beta-amyloid levels: high amounts of beta-amyloid in the brain can aggregate to form plaques and stop cells from communicating. Plaque formation kills cells, triggering the development of Alzheimer’s disease.
Cannabinoids, mainly THC, work on blocking the ...
The most common ways people use cannabis used to treat glaucoma are either by smoking cannabis or ingesting CBD oil.
Nevertheless, cannabis can be used in the following forms:
1- Smoking: this is the quickest way to get the effect of cannabis. It can be rolled into a cigarette or smoked in a water pipe, either as herbal cannabis or hash. When it is inhaled, THC would need between 1 to 10 minutes to ...
There is no official recommended dosage of cannabis for Alzheimer’s disease. The dosing would vary depending on your condition, weight, sex, and age. It's important to always consult your doctor before using cannabis to avoid taking the wrong dose.
Given that the use of CBD is a relatively new treatment option, healthcare providers are still learning about the appropriate dosages of CBD and are trying to determine what dosing is safe and effective.
CBD and THC have the same chemical formula, but the atoms are arranged differently. This difference in atom position takes away the effect of feeling “high,” from CBD. Hence, CBD has little or no effect on cognition compared to THC.
Smoking cannabis might have some negative side effects. That is why doctors recommend CBD oil rather than smoking cannabis for medical purposes. These harmful effects might include developing:
- Respiratory problems: smoking cannabis can irritate the ...
- Chuanhai, C., Yaqiong, L., Hui, L., Ge, B., Jonathan, M., Xiaoyang, L., . . . Jianfeng, C. (2014). The Potential Therapeutic Effects of THC on Alzheimer's Disease. Journal of Alzheimer's Disease,42(3), 973-984.
- Eubanks, L. M., Rogers, C. J., Beuscher, Koob, G. F., Olson, A. J., Dickerson, T. J., & Janda, K. D. (2006). A Molecular Link between the Active Component of Marijuana and Alzheimer’s Disease Pathology. Molecular Pharmaceutics,3(6), 773-777. doi:10.1021/mp060066m
- Jin, S., Kedia, N., Illes-Toth, E., Haralampiev, I., Prisner, S., Herrmann, A., . . . Bieschke, J. (2016). Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity. Journal of Biological Chemistry,291(37), 19590-19606. doi:10.1074/jbc.m115.691840
- Watt, G., & Karl, T. (2017). In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimers Disease. Frontiers in Pharmacology,8. doi:10.3389/fphar.2017.00020
Cannabis | CBD For Alzheimer
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