This research rejects the claim that Zinc is effective for the treatment of acne. This study suggests that topical zinc therapy alone is not of significant benefit in the treatment of acne vulgaris.
Topical zinc therapy for acne vulgaris
April 1985
R J Cochran, S B Tucker, S A Flannigan
Abstract
A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne lesions. The irritancy due to topically applied zinc was significantly greater (p less than or equal to 0.05) than that due to the placebo. Zinc serum levels were not significantly elevated between the two regimens before, during, or after treatment. This study suggests that topical zinc therapy alone is not of significant benefit in the treatment of acne vulgaris.
