Peripheral artery disease is similar to coronary artery disease (CAD).

Peripheral artery disease is a narrowing of the peripheral arteries that carry blood away from the heart to other parts of the body. The most common type is lower-extremity PAD, in which blood flow is reduced to the legs and feet. 

Both PAD and coronary artery disease are caused by atherosclerosis, the buildup of fatty plaque in the arteries that narrows and blocks them throughout the body, including in the heart, brain, arms, legs, pelvis and kidneys. 

 

Quick facts about PAD

The most common symptoms of lower-extremity PAD are cramping, fatigue, aching, pain or discomfort in the leg or hip muscles while walking or climbing stairs. This pain usually goes away with rest and returns when you walk again. 

Be aware that:

  • Many people mistake the symptoms of PAD for something else.
  • PAD often goes undiagnosed by health care professionals.
  • People with peripheral artery disease have a higher risk of coronary artery disease, heart attack and stroke.
  • Left untreated, PAD can lead to gangrene and amputation.