April 2021

In this video we look at two papers related to how the circadian clock affects the supplements to take and what this means for the best time to take them. The first is a of a study where the authors set up a mathematical model which follows the interactions of some of the key genes related to NAD and SIRT1 such as mTORC1, Insulin/IGF1. Based on this it predicts the effects of taking resveratrol or an NAD booster at various times of the day. 
The second paper investigates how the timing of a calcium supplement affects the resorption of bone. 

Papers
Aging affects circadian clock and metabolism and modulates timing of medication
https://www.sciencedirect.com/science...

The effect of calcium supplementation on the circadian rhythm of bone resorption 
https://pubmed.ncbi.nlm.nih.gov/8077353/

Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.  Products or services mentioned in this video are not a recommendation.

Disclosure: Some of the links provided are affiliate links.  Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel.

CIRCLE DNA TEST 30% DISCOUNT (DNA Test, Not a Biological Age Test)
https://ambassador.circledna.com/l/13...
In an earlier video I mentioned that we got our DNA tested We used a company called Circle based in HK but serve worldwide, which has given our listeners a 30% DISCOUNT through the above link.

BIOLOGICAL AGE TEST 10% OFF: 
Link outside of North America 
https://epi-age.com/?epi=modern.healt... 

Link for Canada 
https://epigenexperts.ca/?epi=modern.... 
Link for the US 
https://epiagingusa.com/?wpam_id=13​​ 
Discount coupon code is modernhealthspan 
Expiration date is April 30, 2022. 
NOTE: The coupon cannot be used in conjunction with any other coupons and is subject to the company's approval.
SUPPLEMENT LIST:
NMN Pro 300 Enhanced Absorption Capsule – ProHealth https://amzn.to/38W2hGR
NMN Lozenges 250mg - X 4 ProHealth https://amzn.to/2ycVfhE​​
Pro Powder (15 Grams) – ProHealth https://amzn.to/3r4jpjT​​
100% Trans-Resveratrol 1000 mg ProHealth https://amzn.to/2yeBM04​​
Alpha Lipoic Acid 600 mg - Doctor's Best https://tinyurl.com/yb68chzo​​
Vitamin C 1g – California Gold Nutrition https://iherb.co/tjmJCSKv​​
D3/K2 – Thorne - https://iherb.co/GYkP4T5b​​
Krill Oil BulletProof– EPA/DHA – https://amzn.to/314600B​​
TMG Powder https://amzn.to/3hhtiGB​​
Celery Seed, 505 mg, 100 VegCaps https://iherb.co/BvKGp8p2​​
Folate and Vit B12 https://amzn.to/2X9SiXX​​
CoQ10 - Ubiquinol - https://amzn.to/2JDxJjN​​
Acacia fibre - https://amzn.to/2X2yzJN​​
TMG 1000mg tablets https://amzn.to/3q1SNAc​​