Medical Author: William C. Shiel Jr., MD, FACP, FACR

Nausea is the sensation of an urge to vomit. Nausea can be acute and short-lived, or it can be prolonged. When prolonged, it is a debilitating symptom. Nausea (and vomiting) can be psychological or physical in origin. It can originate from problems in the brain or organs of the upper gastrointestinal tract (esophagus, stomach, small intestine, liver, pancreas, and gallbladder). Nausea also may be caused by diseases of many organs outside of the gastrointestinal system. Therefore, the diagnosis of the cause of prolonged nausea may not be easy. All stimuli that cause nausea work via the vomiting center in the brain, which gives rise to the sensation of nausea and coordinates the physical act of vomiting.