Importance of n−3 fatty acids in health and disease

January 2000
William E Connor

ABSTRACT

In the past 2 decades, views about dietary n−3 fatty acids have moved from speculation about their functions to solid evidence that they are not only essential nutrients but also may favorably modulate many diseases.

Docosahexaenoic acid (22:6n−3), which is a vital component of the phospholipids of cellular membranes, especially in the brain and retina, is necessary for their proper functioning. n−3 Fatty acids favorably affect atherosclerosis, coronary heart disease, inflammatory disease, and perhaps even behavioral disorders.

The 38 articles in this supplement document the importance of n−3 fatty acids in both health and disease.