Dosing & Uses

 

Dosage Forms & Strengths
Tablet:

  • 400mcg
  • 800mcg
  • 1mg

Injectable solution:

  • 5mg/mL

 

Nutritional Supplementation

Recommended daily allowance (RDA)

  • Males: 400 mcg/day PO
  • Females: 400-800 mcg/day PO
  • Pregnant women: 600 mcg/day PO
  • Nursing women: 500 mcg/day PO
  • Upper limit: 1 mg/day PO

 

Neural Tube Defects Prophylaxis

  • Females of childbearing potential: 400 mcg/day PO
  • Pregnancy women: 600 mcg/day PO
  • Females with high risk or family history of neural tube defects: 4 mg/day PO

 

Folic Acid Deficiency

  • 0.4-1 mg PO/IV/IM/SC once daily

 

Methanol Toxicity

  • 50-75 mg IV q4hr for 24 hr

 

Methotrexate Toxicity Prophylaxis (Off-label)

  • 1 mg PO qDay; may increase up to 5 mg/day if toxicity emerges