Ready to leave?
Oops ! Condition name you have entered is invalid.
You are now leaving Aposbook.com and going to an external site managed by another organization.
Please confirm your email address and try to login again.
This account has been deleted. do you want to restore it?
A verification link will be sent to within the next 2 minutes. Please click it to validate your e mail.
*If you didn't get the link, please check your spam folder
You are now a registered user.
Once you log in, you can use our search tool to find all the natural solutions for any health condition. Plus, you can discuss, ask questions, and share your point of view about various topics.
We highly encourage you to write reviews and testimonials about any natural solution you have tried. Regardless of whether the solution was effective or not, we urge you to remain authentic and objective. Our ultimate aim is to help each other learn the truth about each solution. You can also add content you may find interesting in the library center section.
Together, we can contribute to our community’s knowledge.
Sincerely,
The Aposbook Team
A validation link will be sent to you by email. Please confirm your address to log in
*If you didn't get the link, please check your spam folder
Please log in to use this feature
Your account has been suspended because you have violated our code of conduct. If you think this was a mistake, you can contact us by email at: support@aposbook.com "Contact us" form.
Success! Thank you for your feedback. Your contribution can make a difference. Together we can help each other.
2017 Aug
Laura Y Zuñiga, Manuel González-Ortiz, Esperanza Martínez-Abundis
Abstract
Gymnema sylvestre is a medicinal plant whose consumption has demonstrated benefits on lipid and glucose levels, blood pressure, and body weight (BWt). The aim of this study was to evaluate the effect of G. sylvestre administration on metabolic syndrome (MetS), insulin secretion, and insulin sensitivity. A randomized, double-blind, placebo-controlled clinical trial was carried out in 24 patients (without pharmacological treatment), 30-60 years old, with diagnosis of MetS in accordance with the modified International Diabetes Federation criteria. Patients were randomly assigned to receive G. sylvestre or placebo twice daily before breakfast and dinner in 300 mg capsules for a total of 600 mg per day for 12 weeks. Before and after the intervention, the components of MetS were evaluated as well as BWt, body mass index (BMI), total cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein (VLDL). Area under the curve of glucose and insulin, phases of insulin secretion, and insulin sensitivity were calculated. Statistical analysis was performed using Wilcoxon signed-rank, Mann-Whitney U, and chi-square tests; P ≤ .05 was considered statistically significant. After G. sylvestre administration, significant decreases in BWt (81.3 ± 10.6 kg vs. 77.9 ± 8.4 kg, P = .02), BMI (31.2 ± 2.5 kg/m2 vs. 30.4 ± 2.2 kg/m2, P = .02), and VLDL levels (0.45 ± 0.15 mmol/dL vs. 0.35 ± 0.15 mmol/dL, P = .05) were observed, without modifying the components of MetS, insulin secretion, and insulin sensitivity. In conclusion, G. sylvestre administration decreased BWt, BMI, and VLDL levels in subjects with MetS, without changes in insulin secretion and insulin sensitivity.
Gymnema sylvestre for Diabetes: From Traditional Herb to Future's Therapeutic
An open label study on the supplementation of Gymnema sylvestre in type 2 diabetics